Blog and Knowledge Database
Publications

DirectSens & University of Galway Publish in ACS Electrochemistry: Oxygen-Independent L-Lactate Sensing
We’re proud to announce the publication of our latest research in ACS Electrochemistry. This work was performed in partnership between the University of Galway and DirectSens Biosensors GmbH “An oxygen-insensitive electrochemical biosensor for L-lactate using a novel FMN-dependent lactate dehydrogenase” Reshma Kidayaveettil*, Christopher Schulz° , Alfons K. G. Felice°, Leander

A microneedle-based, integrated smart patch for continuous biomarker monitoring
Microneedle-Based Smart Patch for Continuous Biomarker Monitoring At Microneedles 2025, our consortium presented exciting results from the ELSAH project: the development of an integrated microneedle (MN)-based smart patch designed for continuous monitoring of biomarkers such as glucose and lactate. Why Microneedle Monitoring? Chronic conditions such as diabetes, cardiovascular diseases, and

Flavin Mononucleotide-Dependent l-Lactate Dehydrogenases: Expanding the Toolbox of Enzymes for l-Lactate Biosensors
The study explain the advantages of LDH Lactazymes, especially those on flavin mononucleotide (FMN)-dependent L-lactate dehydrogenases for biosensor applications. It investigates seven newly discovered enzymes for L-lactate detection and compares their performance to Aerococcus viridans LOx. The research emphasizes enzyme diversity in biosensors, focusing on enhancing sensitivity and stability for
Technology

DirectSens & University of Galway Publish in ACS Electrochemistry: Oxygen-Independent L-Lactate Sensing
We’re proud to announce the publication of our latest research in ACS Electrochemistry. This work was performed in partnership between the University of Galway and DirectSens Biosensors GmbH “An oxygen-insensitive electrochemical biosensor for L-lactate using a novel FMN-dependent lactate dehydrogenase” Reshma Kidayaveettil*, Christopher Schulz° , Alfons K. G. Felice°, Leander

Flavin Mononucleotide-Dependent l-Lactate Dehydrogenases: Expanding the Toolbox of Enzymes for l-Lactate Biosensors
The study explain the advantages of LDH Lactazymes, especially those on flavin mononucleotide (FMN)-dependent L-lactate dehydrogenases for biosensor applications. It investigates seven newly discovered enzymes for L-lactate detection and compares their performance to Aerococcus viridans LOx. The research emphasizes enzyme diversity in biosensors, focusing on enhancing sensitivity and stability for

Why Oxygen-Independent Enzyme Technology Simplifies In-Vivo Monitoring
Imagine if you could conduct complex biochemical reactions without relying on oxygen—a key player in many biological processes. Sound impossible? Well, thanks to advances in enzyme technology, this is becoming a reality. Enter the world of oxygen-independent enzymes, an exciting development that’s set to revolutionize biotechnology and medical diagnostics. Oxygen-Independent
General

How Accurate Lactate Testing Can Improve Clinical Outcomes
Lactate—this word might bring back memories of high school chemistry or that burning sensation in your muscles after an intense workout. But lactate is more than just a byproduct of physical exertion; it’s a crucial biochemical player with significant implications in clinical medicine. In this article, we’re diving deep into

5 Common Stability Challenges in Lactate Sensors And How To Overcome Them
Ever wonder why lactate sensors are such a big deal? Whether you’re an athlete keeping tabs on your performance, a healthcare pro diagnosing conditions, or just a tech enthusiast, these little gadgets play a vital role. But here’s the thing: keeping them stable and reliable isn’t always a walk in

Interesting Facts About Enzymes And Their Role In Lactate Detection
Enzymes: Nature’s Biological Catalysts Imagine if you had a tiny superhero living inside you, tirelessly working around the clock to keep your body functioning smoothly. Well, guess what? You do! These superheroes are called enzymes, and they play a crucial role in just about every biological process that keeps us
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